When is the right time to stop taking antibiotics?

Press coverage has picked up on an interesting paper The antibiotic course has had its day published in the British Medical Journal (online 26th July 2017). The paper was of interest to me as I studied antibiotic resistance for my PhD, and this topic was also the theme of (to date) my only appearance on TV news.

bmjab

As anyone who has ever been prescribed antibiotics ought to know, current clinical practice from the World Health Organisation and others recommends completion of the course (often 7 days), even if the patient feels better sooner. The justification for this strategy has been concern that premature ending of treatment might allow the disease-causing bacteria to recover and continue to wreak havoc, possibly in a newly-resistant manner.

In the new paper, Martin Llewelyn (Brighton and Sussex Medical School) and colleagues from a number of institutions in South-East England question the basis of this recommendation. Whereas the link between exposure to antibacterials and the development of resistance is well documented, these authors wondered about the origins of the original advice. They suggest that the requirement to “complete the course” probably stands on little more than the anecdotal experience of some of the antibiotic pioneers. Continue reading

My unexpected debut on BBC TV

bbc3

My day was not scheduled to include a spot on News24

As I headed into work on Wednesday 2nd July, I had no idea that by the time I came home that evening I would have done two live interviews at New Broadcasting House, headquarters of the BBC.

I’ve done several radio interviews previously and have been in discussion with¬†makers¬†of The Big Questions on at least three occasions about appearing on that show (one of which, tellingly, ended when the researcher declared I was “a bit too in the middle on the issue”). However this was to be my first experience of being on television.

I was due to have an admin splurge in my office, before a scheduled trip to London in the afternoon for a trustees’ meeting. The news that morning had included an announcement by David Cameron that there a new review was to be set up, looking into ways to tackle antibiotic resistance (see Antibiotic resistance: Cameron warns of medical ‘dark ages’).

I give final year undergraduate lectures on antibiotic resistance, so it is a topic about which I maintain an active interest. I was piqued by this announcement since it smacked of the Prime Minister climbing aboard the growing movement to tackle the problem (which IS serious, in case you were in any doubt), and because a call for a review inevitably means it will be even longer before actual steps are taken. The need for new antibiotics was known 20-odd years ago when I was doing a PhD on resistance to a major class of antibacterials and since then the situation has got worse, not better. Continue reading

  • Awards

    The Power of Comparative Genomics received a Special Commendation

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